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DiscoveryProbe™ TGF-beta/Smad Compound Library
60个TGF-β/Smad抑制剂的集合,用于TGF-β/Smad信号通路研究。

DiscoveryProbe™ TGF-beta/Smad Compound Library

产品编号:L1045
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Sample solution is provided at 25 µL, 10mM.

Click and Customize the Panel with your own choices of compounds/size/qtuanties/chemical forms etc.

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质量控制

相关生物数据

Enzastaurin (LY317615)

相关生物数据

Enzastaurin (LY317615)

相关生物数据

Y-27632

相关生物数据

Nilotinib

相关生物数据

Nilotinib

Signaling Pathway

Bcr-Abl Compare Products
TGF-βR1(ALK5) Compare Products
ROCK Compare Products

Featured Products of the Library

Catalog No. Product Name Summary Targets CAS Number Smiles
A1670 Enzastaurin (LY317615) PKC beta inhibitor,potent and selective PKC 170364-57-5 CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)C6CCN(CC6)CC7=CC=CC=N7
A1805 Imatinib Mesylate (STI571) Abl/c-kit/PDGFR inhibitor Bcr-Abl 220127-57-1 CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O
A2133 Saracatinib (AZD0530) Src/Abl inhibitor,potent and selective Bcr-Abl 379231-04-6 CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
A3008 Y-27632 dihydrochloride ROCK1 inhibitor ROCK 146986-50-7;129830-38-2 CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N
A5602 SB525334 (TGF-beta1) receptor inhibitor TGF-βR1(ALK5) 356559-20-1 CC1=CC=CC(=N1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=NC=CN=C4C=C3
A8249 SB 431542 ALK inhibitor TGF-βR1(ALK5) 301836-41-9 C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
A8342 GF 109203X Protein kinase C,MLCK,PKG and PKA inhibitor PKC 133052-90-1 CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
A8348 LY2157299 TGF-βR1 inhibitor,potent and selective TGF-βR1(ALK5) 700874-72-2 CC1=CC=CC(=N1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N
Download the TGF-beta-Smad-Compound-Library - XLSX       Download the TGF-beta-Smad-Compound-Library - SDF

Advantages

  • Available in stock with overnight delivery and free shipping over $500
  • Cost-effective and competitive price to save your findings
  • Potent, selective and cell-permeable in inhibiting or activating target molecules
  • Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
  • Detailed files describing potency, selectivity and applications etc.
  • Supported by published data from top peer-reviewed journals
  • Guaranteed high quality with NMR and HPLC validation

Storage and Shipping Information

Form Pre-dissolved DMSO solutions Stability -20°C: 3 months
-80°C: 6 months
Packaging 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.
General tips For obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Compound Library Composition